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Working Group Pathobiology Work-Plan 2008
The OECI Pathobiology working group has the task to standardise and harmonize the pathology in European cancer centers. In addition, it is seen as an important task to spread innovative knowledge amongst the pathology departments of the OECI members.

The program started with the implementation of TuBaFrost. TuBaFrost is a complete infrastructure for a European Tumor Tissue Bank ( The network was developed in a three-year fifth-framework program of the European Commission involving OECI members as participants as well as the EORTC and a Dutch law firm.

OECI members can now utilise this virtual tissue bank to share their frozen tumor tissue collections with the other OECI members and perhaps even with external institutes with the intention to stimulate cooperation through the build up of a sufficient critical mass for multi-center translational cancer research. Special care has been taken in the access rules including incentives for the collecting institutes. Governance over the samples as well as the samples stays at the collecting institute. The institute can decide using their normal procedures to join or reject a request from the network. It allows local negotiations on cooperation, co publication or compensation in costs.

In spring 2007 this working group organised an OECI workshop on European tissue banking with a focus on TuBaFrost for the introduction of this program.

Plans are under development to set up an OECI platform for innovative, interesting and difficult histology cases using Virtual Microscopy to present the complete histology for every case on the Internet complete with an Internet discussion forum to discuss the different cases on a European level. Cases that have been thoroughly discussed, which is to be decided by the moderator of the case and in yearly meetings can be preserved and will serve as a reference set which can be used for education purposes.

There is also a need for harmonization of Molecular Pathology, we hope to attract a European project in FP 7 to set up a proper exchange program for molecular diagnostic personnel of the OECI members and perhaps set up a program for material exchange for the implementation of European quality control in the different OECI molecular Pathology labs to improve overall outcome.

December 2007

WG Pathobiology

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